Article
Profile of esophageal squamous cell carcinoma mutations in Brazilian patients.
Scientific reports - 18 Oct 2021
Munari Fernanda Franco, Dos Santos Wellington, Evangelista Adriane Feijó, Carvalho Ana Carolina, Pastrez Paula Aguiar, Bugatti Diego, Wohnrath Durval R, Scapulatempo-Neto Cristovam, Guimarães Denise Peixoto, Longatto-Filho Adhemar, Reis Rui Manuel
Abstract excerpt
Esophageal cancer is an aggressive tumor that has a high rate of incidence and mortality worldwide. It is the 10th most frequent type in Brazil, being squamous cell carcinoma (ESCC) the predominant subtype. There is currently an incessant search to identify the frequently altered genes associated with esophageal squamous cell carcinoma biology that could be druggable. This study aimed to analyze the somatic...
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