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Article

Alterations of the TP53 gene in gastric and esophageal carcinogenesis.

Journal of biomedicine & biotechnology - 1 Jan 2012

Bellini Marilanda Ferreira, Cadamuro Aline Cristina Targa, Succi Maysa, Proença Marcela Alcântara, Silva Ana Elizabete

Abstract excerpt

TP53 genes is one of more important tumor suppressor gene, which acts as a potent transcription factor with fundamental role in the maintenance of genetic stability. The development of esophageal and gastric cancers is a multistep process resulting in successive accumulation of genetic alterations that culminates in the malignant transformation. Thus, this study highlights the participation of the main genetic...

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Source

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Identifiers

PMID: 22919278
DOI: 10.1155/2012/891961
PMCID: PMC3420349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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