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Article

Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.

Cell - 19 Oct 2001

Billuart P, Winter C G, Maresh A, Zhao X, Luo L

Abstract excerpt

Mechanisms that regulate axon branch stability are largely unknown. Genome-wide analyses of Rho GTPase activating protein (RhoGAP) function in Drosophila using RNA interference identified p190 RhoGAP as essential for axon stability in mushroom body neurons, the olfactory learning and memory center. p190 inactivation leads to axon branch retraction, a phenotype mimicked by activation of GTPase RhoA and its...

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PMID: 11672527
DOI: 10.1016/s0092-8674(01)00522-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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