Article
TGF-beta signals regulate axonal development through distinct Smad-independent mechanisms.
Development (Cambridge, England) - 1 Dec 2008
Ng Julian
Abstract excerpt
Proper nerve connections form when growing axons terminate at the correct postsynaptic target. Here I show that Transforming growth factor beta (TGFbeta) signals regulate axon growth. In most contexts, TGFbeta signals are tightly linked to Smad transcriptional activity. Although known to exist, h...
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