Article
Rho and Ras GTPases in axon growth, guidance, and branching.
Cold Spring Harbor perspectives in biology - 1 Feb 2010
Hall Alan, Lalli Giovanna
Abstract excerpt
The establishment of precise neuronal cell morphology provides the foundation for all aspects of neurobiology. During development, axons emerge from cell bodies after an initial polarization stage, elongate, and navigate towards target regions guided by a range of environmental cues. The Rho and Ras families of small GTPases have emerged as critical players at all stages of axonogenesis. Their ability to...
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