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Article

Alterations at the Ink4a locus in transplacentally induced murine lung tumors.

Cancer letters - 22 Oct 2001

Mizesko M C, Grewe C, Grabner A, Miller M S

Abstract excerpt

The malignant phenotype results from multiple genetic alterations, including the activation of oncogenes and inactivation of tumor suppressor genes. Activation of the Ki-ras oncogene has been implicated as an early event in the pathogenesis of lung adenocarcinomas in humans and experimental animal models. Previous studies from this laboratory have shown that, following treatment of pregnant [D2 x B6D2F(1)]F(2) or...

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Source

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PMID: 11595130
DOI: 10.1016/s0304-3835(01)00647-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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