Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular pathways in malignant pleural mesothelioma.

Cancer letters - 8 Aug 2006

Whitson Bryan A, Kratzke Robert A

Abstract excerpt

Malignant pleural mesothelioma, although uncommon, is highly lethal. There is a high correlation between associated environmental exposure factors, carcinogens, and its development. Carcinogenesis is also mediated by genetic defects that result in loss of tumor suppressors or over expression of proto-oncogenes. Factors such as the loss of CDK inhibition function, IGF stimulatory pathways, p14(ARF), p15(INK4b),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Pleural Neoplasms
Share to Mesothelioma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Source

Identifiers

PMID: 16216411
DOI: 10.1016/j.canlet.2005.08.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular pathways in malignant pleural mesothelioma.PMID 16216411Read ↗

Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors.Semantic proximity Read ↗

DNA repair and damage pathways in mesothelioma development and therapySemantic proximity Read ↗

Advances in the molecular biology of malignant mesothelioma.Semantic proximity Read ↗

Molecular Changes in Mesothelioma With an Impact on Prognosis and TreatmentSemantic proximity Read ↗

Deciphering signaling pathway interplay via miRNAs in malignant pleural mesotheliomaSemantic proximity Read ↗

Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells.Semantic proximity Read ↗

Molecular biology of malignant mesotheliomaSemantic proximity Read ↗

Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis.Semantic proximity Read ↗

The role of key genes and pathways involved in the tumorigenesis of Malignant MesotheliomaSemantic proximity Read ↗

Molecular biology of malignant mesothelioma: a review.Semantic proximity Read ↗

Biological agents involved in malignant mesothelioma: relevance as biomarkers or therapeutic targets.Semantic proximity Read ↗

Update on the molecular biology of malignant mesotheliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.