Article
Activated Ki-ras proto-oncogene in spontaneously transformed and chemical tumor-derived cell lines related to the mouse lung alveologenic carcinoma.
Molecular carcinogenesis - 1 Jan 1990
Leigh D A, Ferguson V, Bentel J M, Miller J O, Smith G J
Abstract excerpt
An in vitro cell model of mouse lung alveologenic carcinoma consisting of preneoplastic nonmalignant cells, spontaneously transformed cells, and urethane-induced malignant cells was analyzed for phenotypic and genotypic changes associated with the transition to neoplasia. The polymerase chain rea...
Topics
- Adenocarcinoma, Bronchiolo-Alveolar
- Adenoma
- Animals
- Base Sequence
- Cell Transformation, Neoplastic
- Codon
- Lung Neoplasms
- Mice
- Molecular Sequence Data
- Mutation
- Neoplasm Metastasis
- Neoplasm Transplantation
- Oligonucleotides
- Oncogenes
- Polymerase Chain Reaction
- Proto-Oncogene Proteins p21(ras)
- RNA, Messenger
- RNA, Neoplasm