Article
Gender‐Related Differences in the Rates of Age AssociatedThymic Atrophy
1 Jan 2001
Abstract excerpt
Age associated thymic atrophy has been shown to be linked to problems with rearrangement of the beta chain of the T cell receptor (TCR) in male mice during the early phases of the intrathymic T cell developmental pathway. In this study, thymic atrophy in female mice was found to occur at a different rate than in male mice. At 9 months of age there was a significantly greater number of cells in the thymus of...
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