Article
Age-related thymic involution in C57BL/6J x DBA/2J recombinant-inbred mice maps to mouse chromosomes 9 and 10.
Genes and immunity - 1 Sept 2003
Hsu H-C, Zhang H-G, Li L, Yi N, Yang P-A, Wu Q, Zhou J, Sun S, Xu X, Yang X, Lu L, Van Zant G, Williams R W, Allison D B, Mountz J D
Abstract excerpt
A comprehensive analysis of initial thymus size and involution rate has not been quantitated for different genetic backgrounds of mice, thus genetic linkage analysis of thymic involution has not been possible. Here, we have used a mathematical method to analyze the age-related decline in thymocyt...
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