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Article

The effect of age on the phenotype and function of developing thymocytes.

Journal of comparative pathology - 1 Jan 2010

Aw D, Silva A B, Palmer D B

Abstract excerpt

The immune system declines with age leading to a progressive deterioration in the ability to respond to infection and vaccination. Age-associated thymic involution is one of the most recognized changes in the ageing immune system and is believed to be a major contributor towards immunosenescence; however, the precise mechanisms involved in age-associated thymic involution remain unclear. In order to gain further...

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Identifiers

PMID: 20003987
DOI: 10.1016/j.jcpa.2009.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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