Article
Phenotypical and morphological changes in the thymic microenvironment from ageing mice.
Biogerontology - 1 Jun 2009
Aw Danielle, Taylor-Brown Frances, Cooper Kate, Palmer Donald B
Abstract excerpt
The thymus is crucial for T-cell output and the age-associated involution of this organ, is thought to have a major impact in the decline in immunity that is seen in later life. The mechanism that underlines thymic involution is not known, however, we have evidence to suggest that this is may be due to changes in the thymic microenvironment. To further test this hypothesis, we quantified the in situ changes to...
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