Prepubertal castration alters the phenotypic profile of adult rat thymocytes.

doi:10.1159/000096878

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Article

Prepubertal castration alters the phenotypic profile of adult rat thymocytes.

Neuroimmunomodulation - 1 Jan 2000

Leposavic G, Karapetrovic B, Micic M, Kosec D

Abstract excerpt

To assess the gonadal influence on the maturation of the thymus, rats were orchidectomized at different periods critical for programming of both gonadal and immune functions, and the composition of the intrathymic thymocyte population was determined in adults by flow cytometric analysis of the surface phenotype. The relative proportion of thymocytes expressing CD4, CD8 and T cell receptor (TCR)alpha beta was...

Topics

Age Factors
Animals
Castration
Cell Count
Flow Cytometry
Male
Phenotype
Rats
Rats, Inbred Strains
T-Lymphocytes
Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 8521138
DOI: 10.1159/000096878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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