Article
Differential effects of gonadectomy on the thymocyte phenotypic profile in male and female rats.
Pharmacology, biochemistry, and behavior - 1 May 1996
Leposavić G, Karapetrović B, Obradović S, Vidiíc Dandović B, Kosec D
Abstract excerpt
As an organ responsible for generation of T-cell repertoire the thymus occupies a central position in establishment of mature immune response. To assess the potential role of the gonadal steroids in development and maintenance of immunological sexual dimorphism, the effects of gonadectomy pre- and postpuberty on the thymocyte profile of male and female rats were examined. Rats aged 30 days or 75 days were...
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