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Article

Physical and functional interactions of human DNA polymerase eta with PCNA.

Molecular and cellular biology - 1 Nov 2001

Haracska L, Johnson R E, Unk I, Phillips B, Hurwitz J, Prakash L, Prakash S

Abstract excerpt

Human DNA polymerase eta (hPoleta) functions in the error-free replication of UV-damaged DNA, and mutations in hPoleta cause cancer-prone syndrome, the variant form of xeroderma pigmentosum. However, in spite of its key role in promoting replication through a variety of distorting DNA lesions, the manner by which hPoleta is targeted to the replication machinery stalled at a lesion site remains unknown. Here, we...

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Share to DNA Damage
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proliferating Cell Nuclear Antigen

Share to Replication Protein A

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Source

Open in PubMed Open full text

Identifiers

PMID: 11585903
DOI: 10.1128/MCB.21.21.7199-7206.2001
PMCID: PMC99895

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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