Article
Human Kaposi's sarcoma herpesvirus processivity factor-8 functions as a dimer in DNA synthesis.
The Journal of biological chemistry - 2 Jul 2004
Chen Xulin, Lin Kai, Ricciardi Robert P
Abstract excerpt
In the absence of other proteins, the DNA polymerase (Pol-8) of Kaposi's sarcoma herpesvirus incorporates only several nucleotides from a primer template. However, association with the Kaposi's sarcoma herpesvirus processivity factor (PF-8) enables Pol-8 to incorporate thousands of nucleotides. Unlike the well described sliding clamp processivity factors, eukaryotic proliferating cell nuclear antigen and...
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