Article
Histological and functional analysis of vascular smooth muscle cells in a novel culture system with honeycomb-like structure.
Atherosclerosis - 1 Oct 2001
Ishii I, Tomizawa A, Kawachi H, Suzuki T, Kotani A, Koshushi I, Itoh H, Morisaki N, Bujo H, Saito Y, Ohmori S, Kitada M
Abstract excerpt
Vascular smooth muscle cells (SMCs) undergo phenotype change with the development of atherosclerosis. The phenotype changes of SMCs have been observed in various culture conditions, such as collagen-coated dishes. Here, we report the morphological and functional features of SMCs in a novel culture system using type I-collagen in a characteristic three-dimensional structure designated as honeycombs. The number of...
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