Article
Cultured myofibroblasts display a specific phenotype that differentiates them from fibroblasts and smooth muscle cells.
Dermatology (Basel, Switzerland) - 1 Jan 1994
Lefebvre P, Nusgens B V, Lapière C M
Abstract excerpt
BACKGROUND: Myofibroblasts (MF) from human granulation tissue derive from perilesional cells and display similarities with fibroblasts (DF) and smooth muscle cells (SMC). OBJECTIVE: Determine additional markers to assess the phenotype of MF. METHODS: MF, DF and SMC derived from human tissues were amplified in culture. Their phenotype and response to various regulatory processes were compared in vitro. RESULTS: MF...
Topics
- Cells, Cultured
- Collagen
- Cytoskeletal Proteins
- Fibroblasts
- Granulation Tissue
- Humans
- Muscle, Smooth, Vascular
- Phenotype
- RNA, Messenger