Article
Phenotypic and functional transformation in smooth muscle cells derived from varicose veins.
Journal of vascular surgery. Venous and lymphatic disorders - 1 Sept 2017
Xu Yongbo, Bei Yuanyuan, Li Yuan, Chu Haibo
Abstract excerpt
OBJECTIVE: Varicose veins (VVs) are a common disorder of venous dilation and tortuosity, but the underlying mechanism is unclear. The functional integrity and phenotypic differences of VVs are also unclear. This study tested the hypothesis that phenotypic and functional differences exist between smooth muscle cells (SMCs) derived from VVs and normal veins. METHODS: SMCs were isolated from 28 samples of varicose...
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