Article
Innate diversity of adult human arterial smooth muscle cells: cloning of distinct subtypes from the internal thoracic artery.
Circulation research - 14 Sept 2001
Li S, Fan Y S, Chow L H, Van Den Diepstraten C, van Der Veer E, Sims S M, Pickering J G
Abstract excerpt
Vascular smooth muscle cells (SMCs) perform diverse functions and this functional heterogeneity could be based on differential recruitment of distinct SMC subsets. In humans, however, there is little support for such a paradigm, partly because isolation of pure human SMC subsets has proven difficult. We report the cloning of 12 SMC lines from a single fragment of human internal thoracic artery and the elucidation...
Topics
- Actins
- Adult
- Angiotensin II
- Becaplermin
- Blotting, Western
- Calcium
- Calcium-Binding Proteins
- Calmodulin-Binding Proteins
- Cell Division
- Cell Movement
- Cell Size
- Cells, Cultured
- Clone Cells
- Culture Media