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Article

The Phenotypic Responses of Vascular Smooth Muscle Cells Exposed to Mechanical Cues.

Cells - 26 Aug 2021

Jensen Lise Filt, Bentzon Jacob Fog, Albarrán-Juárez Julian

Abstract excerpt

During the development of atherosclerosis and other vascular diseases, vascular smooth muscle cells (SMCs) located in the intima and media of blood vessels shift from a contractile state towards other phenotypes that differ substantially from differentiated SMCs. In addition, these cells acquire new functions, such as the production of alternative extracellular matrix (ECM) proteins and signal molecules. A...

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Identifiers

PMID: 34571858
DOI: 10.3390/cells10092209
PMCID: PMC8469800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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