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Article

Phenotype and function of smooth muscle cells derived from the human normal great saphenous vein in response to hypoxia.

Phlebology - 1 Mar 2024

Chu Haibo, Qin Yanyan, Qiu Tianzhen, Zhou Shunchang, Na Zhang, Sun Yanping, Xu Yongbo, Zhong Yuxu

Abstract excerpt

OBJECTIVE: The contribution of hypoxia to the pathophysiology of vascular smooth muscle cells (VSMCs) has not yet been fully elucidated. This study evaluated the effect of hypoxia on the phenotype and function of SMCs derived from the human normal great saphenous veins (NGSVs). METHODS: Fifteen NGSV tissue samples were collected. SMCs were isolated and cultured. Proliferation, migration, adhesion, senescence, and...

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PMID: 37921696
DOI: 10.1177/02683555231211990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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