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Article

Genomic analysis of smooth muscle cells in 3-dimensional collagen matrix.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2003

Li Song, Lao Jianmin, Chen Benjamin P C, Li Yi-shuan, Zhao Yihua, Chu Julia, Chen Kuang-Den, Tsou Tsui-Chun, Peck Konan, Chien Shu

Abstract excerpt

The proliferation, differentiation, and protein synthesis of vascular smooth muscle cells (SMCs) play important roles in vascular remodeling. Here, we compared the genetic programming and signaling of SMCs in collagen matrix as a three-dimensional (3-D) environment and on a two-dimensional (2-D) surface. By using DNA microarrays with 9600 genes, we showed that 77 genes were expressed more than twofold and 22...

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Identifiers

PMID: 12475912
DOI: 10.1096/fj.02-0256fje

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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