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Article

Genetic background but not metallothionein phenotype dictates sensitivity to cadmium-induced testicular injury in mice.

Toxicology and applied pharmacology - 1 Oct 2001

Liu J, Corton C, Dix D J, Liu Y, Waalkes M P, Klaassen C D

Abstract excerpt

Sensitivity to cadmium (Cd)-induced testicular injury varies greatly among mouse strains. For instance, 129/SvJ (129) mice are highly sensitive while C57BL/6J (C57) mice are refractory to Cd-induced testicular injury. Metallothionein (MT), a Cd-binding protein, is thought to be responsible for the strain susceptibility to Cd toxicity. In this study, MT-I/II knockout (MT-null) and wild-type 129 mice were used to...

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Source

Identifiers

PMID: 11578143
DOI: 10.1006/taap.2001.9262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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