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Article

Strain differences of cadmium-induced toxicity in rats: Insight from spleen and lung immune responses.

Toxicology letters - 10 Aug 2016

Demenesku Jelena, Popov Aleksandrov Aleksandra, Mirkov Ivana, Ninkov Marina, Zolotarevski Lidija, Kataranovski Dragan, Brceski Ilija, Kataranovski Milena

Abstract excerpt

The impact of genetic background on effects of acute i.p. cadmium administration (0.5mg/kg and 1mg/kg) on basic immune activity of spleen and lungs was examined in two rat strains, Albino Oxford (AO) and Dark Agouti (DA), known to react differently to chemicals. More pronounced inhibition of Concanavalin A (ConA)-induced and Interleukin (IL)-2 stimulated spleen cell proliferation as well as higher levels of...

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Identifiers

PMID: 27234498
DOI: 10.1016/j.toxlet.2016.05.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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