Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Refining the mouse chromosomal location of Cdm, the major gene associated with susceptibility to cadmium-induced testicular necrosis.

Pharmacogenetics - 1 Mar 2000

Dalton T P, Miller M L, Wu X, Menon A, Cianciolo E, McKinnon R A, Smith P W, Robinson L J, Nebert D W

Abstract excerpt

Cadmium (Cd++) is a widespread environmental pollutant and classifed as an IARC 'Category I' human carcinogen. Cd++ can also cause severe renal toxicity and may be involved clinically in cardiovascular disease and osteoporosis. Genetic differences in sensitivity to cadmium toxicity have been noted in humans, whereas, among inbred mouse strains, unequivocal genetic data exist. Resistance to cadmium-induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadmium
Share to Genes, Recessive

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Mice, Inbred DBA

Share to Microsatellite Repeats

Share to Necrosis

Share to Proteins

Share to Testis

Source

Identifiers

PMID: 10762002
DOI: 10.1097/00008571-200003000-00006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Refining the mouse chromosomal location of Cdm, the major gene associated with susceptibility to cadmium-induced testicular necrosis.PMID 10762002Read ↗

Cadmium-induced microsatellite instability in the kidneys and leukocytes of C57BL/6J mice.Semantic proximity Read ↗

Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line.Semantic proximity Read ↗

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium.Semantic proximity Read ↗

Ultrafine mapping of Dyscalc1 to an 80-kb chromosomal segment on chromosome 7 in mice susceptible for dystrophic calcification.Semantic proximity Read ↗

Genome-Wide Association Study to Identify Genes Related to Renal Mercury Concentrations in Mice.Semantic proximity Read ↗

Genetic and epigenetic interplay allows rapid transgenerational adaptation to metal pollution in zebrafishSemantic proximity Read ↗

Genetic background but not metallothionein phenotype dictates sensitivity to cadmium-induced testicular injury in mice.Semantic proximity Read ↗

Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative studySemantic proximity Read ↗

Fine mapping of Dyscalc1, the major genetic determinant of dystrophic cardiac calcification in mice.Semantic proximity Read ↗

Molecular analysis of 36 mutations at the mouse pink-eyed dilution (p) locus.Semantic proximity Read ↗

Identification of a locus on mouse chromosome 3 involved in differential susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease.Semantic proximity Read ↗

New Dyscalc loci for myocardial cell necrosis and calcification (dystrophic cardiac calcinosis) in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.