Article

Strain and sex effects on blood accumulation of lead, chromium, and cadmium in strains from the Collaborative Cross mouse population

2025-10-28

Abstract excerpt

Lead (Pb), chromium (Cr), and cadmium (Cd) are heavy metals that contaminate sites throughout North America. Historically, toxicological effects of Pb, Cr, or Cd compounds have been investigated in a hybrid mouse strain, B6C3F1. However, humans have more genetic diversity and population variability in response to toxicants than is represented in this homogeneous mouse model, which leaves genetic effects on dose re...

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Literature Corpus work: daa20034-72ad-55da-8bfc-af52f8f3067a
DOI: 10.1101/2025.10.27.684896

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