Article
Cadmium-induced microsatellite instability in the kidneys and leukocytes of C57BL/6J mice.
Environmental toxicology - 1 Jan 2000
Du Xiaoyan, Lan Tianfeng, Yuan Bao, Chen Jian, Hu Jinping, Ren Wenzhi, Chen Zhenwen
Abstract excerpt
Cadmium is a cytotoxic, carcinogenic, and mutagenic industrial product or byproduct. The correlation between metal exposure and microsatellite instability (MSI) has been reported by several groups. In the present study, 50 C57BL/6J mice at 6 weeks of age were divided into five groups and intraperitoneally injected with 0, 0.25, 0.5, 1, or 2 mg/kg cadmium chloride quaque die alterna for 4 weeks. Then, the liver,...
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