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Article

Allelic expression and interleukin-2 polymorphisms in multiple sclerosis.

Journal of neuroimmunology - 3 Sept 2001

Matesanz F, Fedetz M, Collado-Romero M, Fernández O, Guerrero M, Delgado C, Alcina A

Abstract excerpt

We have investigated the association of two single nucleotide polymorphisms (SNPs) at positions -384 and 114 in the human interleukin-2 (hIL-2) with multiple sclerosis (MS). For two of the -384 genotypes (G/T, T/T), we observed an association with the susceptibility to secondary progressive (SP) course of MS (P=0.005 and P=0.013, respectively). Expression level differences of the IL-2 alleles (between one- and...

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Source

Identifiers

PMID: 11525806
DOI: 10.1016/s0165-5728(01)00354-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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