Article
Allelic selection of human IL-2 gene.
European journal of immunology - 1 Dec 2000
Matesanz F, Delgado C, Fresno M, Alcina A
Abstract excerpt
The allelic expression of mouse IL-2 cannot be definitely extrapolated to what might happen in humans. Therefore, we investigated the regulation of allelic expression of the IL-2 gene in non-genetically manipulated human T lymphocytes by following natural allelic polymorphisms. We found a phenotypically silent punctual change in the human IL-2 at position 114 after the first nucleotide of the initiation codon,...
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