Article
An evaluation of interleukin genes fails to identify clear susceptibility loci for multiple sclerosis.
Journal of the neurological sciences - 1 May 2000
McDonnell G V, Kirk C W, Hawkins S A, Graham C A
Abstract excerpt
Differential expression of interleukins may influence susceptibility to inflammatory diseases such as MS. IL-1a production is increased in MS patients during acute relapse, IL-2 receptor (IL-2R) secretion correlates with disease activity in several inflammatory disorders and is variable in MS. Both IL-4 and IL-10 expression vary significantly with relapse/remission in MS and IL-9 is postulated to inhibit...
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