Article
Association of IL2RA polymorphisms with susceptibility to multiple sclerosis is not explained by missense mutations in IL2RA.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 May 2011
Matiello Marcelo, Weinshenker Brian G, Atkinson Elizabeth J, Schaefer-Klein Janet, Kantarci Orhun H
Abstract excerpt
Genome-wide association studies have identified an association between two intronic single nucleotide polymorphisms (SNPs), rs12722489 and rs2104286, in the interleukin-2 receptor alpha-chain gene (IL2RA) and susceptibility to multiple sclerosis (MS). We studied these SNPs in association with susceptibility to and severity of MS in a population-based cohort of 220 patients from Olmsted County, Minnesota, compared...
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