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Article

Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1beta and IL-1ra production in multiple sclerosis.

Mediators of inflammation - 1 Apr 2003

Schrijver Hans M, van As Jaco, Crusius J Bart A, Dijkstra Christien D, Uitdehaag Bernard M J

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is an autoimmune disorder, with a considerable genetic influence on susceptibility and disease course. Cytokines play an important role in MS pathophysiology, and genes encoding various cytokines are logical candidates to assess possible associations with MS susceptibility and disease course. We previously reported an association of a combination of polymorphisms in the...

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Identifiers

PMID: 12775358
DOI: 10.1080/0962933031000097691
PMCID: PMC1781595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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