Article
Effects of the multiple sclerosis associated -330 promoter polymorphism in IL2 allelic expression.
Journal of neuroimmunology - 1 Mar 2004
Matesanz Fuencisla, Fedetz Maria, Leyva Laura, Delgado Concepción, Fernández Oscar, Alcina Antonio
Abstract excerpt
The -330 IL2 gene promoter polymorphism has been associated with multiple sclerosis (MS) [J. Neuroimmunol. 119 (2001) 101], but the basis underlying this association remains unknown to date. In the present work, we have found that IL2 promoter-luciferase constructs, transfected in Jurkat cell lin...
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