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Article

Role of interleukin 4 in Spanish multiple sclerosis patients.

Journal of neuroimmunology - 1 Nov 2005

Urcelay Elena, Santiago Jose Luis, Mas Ana, Martínez Alfonso, de Las Heras Virginia, Arroyo Rafael, de la Concha Emilio G

Abstract excerpt

Interleukin 4 is a Th2 cytokine with potent anti-inflammatory properties. Protection from autoimmune encephalomyelitis and multiple sclerosis has been achieved with IL-4 therapy and IL-4 deficient mice developed a more severe form of clinical disease. Four polymorphisms within the IL-4 gene are in strong linkage disequilibrium, including one in the promoter at -590, which controls transcriptional activity. An MS...

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Identifiers

PMID: 16169606
DOI: 10.1016/j.jneuroim.2005.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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