Article
Human dopamine transporter gene polymorphism (VNTR) and alcoholism.
American journal of medical genetics - 19 Sept 1997
Parsian A, Zhang Z H
Abstract excerpt
The dopamine transporter (DAT1) is responsible for taking released dopamine back up into presynaptic terminals and terminating dopaminergic activity. It has been shown that cocaine binds to the dopamine transporter and blocks dopamine reuptake in a fashion that correlates with cocaine reward and...
Topics
- Alcoholism
- Alleles
- Carrier Proteins
- Case-Control Studies
- Dopamine
- Dopamine Plasma Membrane Transport Proteins
- Female
- Gene Frequency
- Genotype
- Haplotypes
- Humans
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Minisatellite Repeats
- Nerve Tissue Proteins
- Polymerase Chain Reaction
- Polymorphism, Genetic