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Article

Effect of serotonin receptor gene variants on substance use disorders.

Annals of medicine - 1 Dec 2025

Al-Eitan Laith, Abu Kharmah Hana, Alghamdi Mansour

Abstract excerpt

BACKGROUND: Substance use disorders are multifaceted conditions influenced by both genetic and environmental factors. Serotonergic pathways are known to be involved in substance use disorder susceptibility, with genetic markers within serotonin receptor genes identified as potential risk factors. METHODS: To further explore this relationship, we conducted a study to investigate the association between several...

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Haplotypes
Jordan
Receptor, Serotonin, 5-HT1B
Receptor, Serotonin, 5-HT2A
Receptors, Serotonin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Serotonin, 5-HT3

Substance-Related Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 39731452
DOI: 10.1080/07853890.2024.2445779
PMCID: PMC11703447

Genes

HTR2A
HTR1B
HTR2B
HTR3A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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