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Article

Serotonin transporter (5‐HTT) gene polymorphisms and susceptibility to cocaine dependence among African‐American individuals

1 Sept 2001

Abstract excerpt

Studies indicate that the serotonin system, particularly the serotonin transporter (5-HTT), may modulate the central effects of cocaine. We investigated whether a polymorphism in the 5' promotor region (5-HTTLPR) of the 5-HTT gene confers susceptibility to cocaine dependence. One hundred and ninety-seven cocaine-dependent African-American subjects and 101 controls were studied. Polymerase chain reaction based...

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Identifiers

PMID: 11900612
DOI: 10.1080/13556210020077064

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