Article
Association study of 37 genes related to serotonin and dopamine neurotransmission and neurotrophic factors in cocaine dependence.
Genes, brain, and behavior - 1 Feb 2013
Fernàndez-Castillo N, Roncero C, Grau-Lopez L, Barral C, Prat G, Rodriguez-Cintas L, Sánchez-Mora C, Gratacòs M, Ramos-Quiroga J A, Casas M, Ribasés M, Cormand B
Abstract excerpt
Cocaine dependence is a neuropsychiatric disorder in which both environmental and genetic factors are involved. Several processes, that include reward and neuroadaptations, mediate the transition from use to dependence. In this regard, dopamine and serotonin neurotransmission systems are clearly involved in reward and other cocaine-related effects, whereas neurotrophic factors may be responsible for...
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