Article
DNA variation and psychopharmacology of the human serotonin receptor 1B (HTR1B) gene.
Pharmacogenomics - 1 Nov 2002
Sanders Alan R, Duan Jubao, Gejman Pablo V
Abstract excerpt
One of the neurotransmitter serotonin's receptors, HTR1B, is of interest for many neuropsychiatric traits, illnesses and treatments for multiple reasons, especially its tissue distribution, pharmacological profile and findings from mice lacking the receptor, along with reasons generally implicating serotonin. Eight mutation scans have uncovered sixteen polymorphisms in the coding sequence and surrounding 5'- and...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA
- Genetic Variation
- Humans
- Mental Disorders
- Molecular Sequence Data
- Polymorphism, Genetic
- Psychopharmacology
- Receptor, Serotonin, 5-HT1B
- Receptors, Serotonin