Article
Agonist-dependent repression mediated by mutant estrogen receptor alpha that lacks the activation function 2 core domain.
The Journal of biological chemistry - 5 Oct 2001
Jung D J, Lee S K, Lee J W
Abstract excerpt
Nuclear receptor corepressor (N-CoR) and silencing mediator of retinoid and thyroid hormone receptors (SMRT) form heterogeneous complexes with various histone deacetylases (HDACs). In this report, we found that ER alpha-Delta AF2, a mutant estrogen receptor alpha (ER alpha) deleted for the C-term...
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