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Article

Antisense DNAs as multisite genomic modulators identified by DNA microarray.

Proceedings of the National Academy of Sciences of the United States of America - 14 Aug 2001

Cho Y S, Kim M K, Cheadle C, Neary C, Becker K G, Cho-Chung Y S

Abstract excerpt

Antisense oligodeoxynucleotides can selectively block disease-causing genes, and cancer genes have been chosen as potential targets for antisense drugs to treat cancer. However, nonspecific side effects have clouded the true antisense mechanism of action and hampered clinical development of antisense therapeutics. Using DNA microarrays, we have conducted a systematic characterization of gene expression in cells...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11481453
DOI: 10.1073/pnas.171314398
PMCID: PMC55536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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