Article
Gene expression microarray technologies in the development of new therapeutic agents.
European journal of cancer (Oxford, England : 1990) - 1 Nov 2004
Clarke Paul A, te Poele Robert, Workman Paul
Abstract excerpt
We review in detail how gene expression microarray technology is benefiting all phases of the discovery, development and subsequent use of new cancer therapeutics. Global gene expression profiling is valuable in cancer classification, elucidation of biochemical pathways and the identification of potential targets for novel molecular therapeutics. We exemplify the value in tissue culture and animal models of...
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