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Article

Antimetastatic gene expression profiles mediated by retinoic acid receptor beta 2 in MDA-MB-435 breast cancer cells.

BMC cancer - 28 Oct 2005

Wallden Brett, Emond Mary, Swift Mari E, Disis Mary L, Swisshelm Karen

Abstract excerpt

BACKGROUND: The retinoic acid receptor beta 2 (RARbeta2) gene modulates proliferation and survival of cultured human breast cancer cells. Previously we showed that ectopic expression of RARbeta2 in a mouse xenograft model prevented metastasis, even in the absence of the ligand, all-trans retinoic acid. We investigated both cultured cells and xenograft tumors in order to delineate the gene expression profiles...

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Source

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Identifiers

PMID: 16255778
DOI: 10.1186/1471-2407-5-140
PMCID: PMC1283145

Genes

CTAG2
FABP6
JUN
TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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