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Article

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

22 Dec 1998

Abstract excerpt

The pleiotropic activities of interferons (IFNs) are mediated primarily through the transcriptional regulation of many downstream effector genes. The mRNA profiles from IFN-alpha, -beta, or -gamma treatments of the human fibrosarcoma cell line, HT1080, were determined by using oligonucleotide arrays with probe sets corresponding to more than 6,800 human genes. Among these were transcripts for known IFN-stimulated...

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PMID: 9861020
DOI: 10.1073/pnas.95.26.15623

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