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Article

Analysis of alpha-2-macroglobulin-2 allele as a risk factor in Alzheimer's disease.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Nicosia F, Alberici A, Benussi L, Gasparini L, Ghidoni R, Mazzoli F, Zanetti O, Frisoni G B, Geroldi C, Binetti G

Abstract excerpt

A correlation between a 5-nucleotide deletion polymorphism in the A2M gene and an enhanced risk of developing Alzheimer's disease (AD) was reported. We studied this polymorphism in sporadic AD patients and patients with frontotemporal dementia (FTD) by using an electrophoretical separation of PCR products on a Metaphor gel. Our results did not show any significant difference between A2M-2 allelic frequency (p =...

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Source

Identifiers

PMID: 11455130
DOI: 10.1159/000051274

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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