Article
Identical distribution of the alpha 2-macroglobulin pentanucleotide deletion in subjects with Alzheimer disease and controls in a German population.
American journal of medical genetics - 4 Dec 2000
Bagli M, Papassotiropoulos A, Jessen F, Schmitz S, Rao M L, Maier W, Heun R
Abstract excerpt
Recently, an association between a deletion polymorphism in the alpha 2-macroglobulin gene (A2M) and Alzheimer disease (AD) has been reported. The aim of the present study was to corroborate this association in a German population of 102 AD patients and two control samples of 191 healthy subject and 160 depressed patients. The frequency of the A2M genotype in AD patients was almost identical to that in both...
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