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Article

Genetic association of alpha2-macroglobulin with Alzheimer's disease in a Finnish elderly population.

Annals of neurology - 1 Sept 1999

Myllykangas L, Polvikoski T, Sulkava R, Verkkoniemi A, Crook R, Tienari P J, Pusa A K, Niinistö L, O'Brien P, Kontula K, Hardy J, Haltia M, Pérez-Tur J

Abstract excerpt

Recently, two studies have reported an association between the alpha2-macroglobulin gene on chromosome 12 and late-onset Alzheimer's disease, whereas others have not been able to replicate these findings. By using a prospective population-based study, we have investigated the relation between two polymorphisms in this gene with the presence of the disease and also with the extent of pathological changes in the...

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PMID: 10482269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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