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Article

The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample.

Neuroscience letters - 6 Aug 1999

Crawford F, Town T, Freeman M, Schinka J, Gold M, Duara R, Mullan M

Abstract excerpt

Genetic association has recently been reported between alleles in the alpha-2-macroglobulin (A2M) gene and the occurrence of Alzheimer's disease (AD) in familial and sporadic samples. We have investigated the A2M intronic deletion polymorphism in a case-control study of 295 unrelated clinic and community-based AD cases, and compared these to a sample of 113 unrelated control individuals recruited as part of an...

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Source

Identifiers

PMID: 10462112
DOI: 10.1016/s0304-3940(99)00470-x

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample.PMID 10462112Read ↗

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Identical distribution of the alpha 2-macroglobulin pentanucleotide deletion in subjects with Alzheimer disease and controls in a German population.Semantic proximity Read ↗

Alpha-2 macroglobulin is genetically associated with Alzheimer disease.Semantic proximity Read ↗

Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin.Semantic proximity Read ↗

The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis.Semantic proximity Read ↗

Alpha-2-macroglobulin intronic polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease.Semantic proximity Read ↗

No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.Semantic proximity Read ↗

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On the lack of a clear-cut association between alpha-2-macroglobulin deletion and the risk of Alzheimer disease in Poland.Semantic proximity Read ↗

Alpha2-macroglobulin polymorphism is not associated with AD or AD-type neuropathology in the Japanese.Semantic proximity Read ↗

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