Article
Estimation of the average burst size of Phix174 am3, cs70 for use in mutation assays with transgenic mice.
Environmental and molecular mutagenesis - 1 Jan 2001
Delongchamp R R, Valentine C R, Malling H V
Abstract excerpt
In mutation assays using transgenic mice, with recoverable vectors such as PhiX174 am3, cs70, mutations originate from two sources: (1) in vivo mutations, that is, mutations that were fixed in the mouse, or (2) ex vivo mutations, that is, mutations that were fixed during recovery or plating. When a bacteriophage infects a bacterium, it multiplies and bursts the cell, releasing a number of phages referred to as...
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